A rti go Antibacterial and cytotoxic properties of some plant crude extracts used in Northeastern folk medicine
نویسندگان
چکیده
In the present study, 32 hexane and ethanol extracts of Protium bahianum, P. heptaphyllum, Croton sellowii, C. rhamnifolius, C. jacobinensis, C. micans and Muntingia calabura were screened for antibacterial activity by the disc-diffusion method. Cytotoxicity assays using the brine shrimp Artemia salina Leach as a model were performed to determine lethal doses for 50% of individuals (LC50 μg/mL). Antibacterial activity was found in flowers hexane extracts of M. calabura against B. subtilis, and leaves ethanol extracts against S. aureus and B. subtilis at concentration of 1mg/mL. Among 32 extracts, 19 showed low or no toxicity (LC50 > 250 μg/mL), 6 showed moderate toxicity (LC50 between 80 μg/mL and 250μg/mL), and 7 were highly toxic (LC50 < 80 μg/mL).
منابع مشابه
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